
Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health
A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs). These changes can influence sperm quality and fertilising ability, early embryo development, assisted reproduction outcomes, and long-term health risks…