Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs). These changes can influence sperm quality and fertilising ability, early embryo development, assisted reproduction outcomes, and long-term health risks…

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Lifestyle interventions key to closing life expectancy gap in mental illness

Lifestyle interventions key to closing life expectancy gap in mental illness

Mental health services must urgently increase investment in lifestyle interventions to improve care and help close the 15-year life expectancy gap faced by people with mental illness, a new Lancet Psychiatry Commission report warns.  Lifestyle interventions targeting physical activity, nutrition, sleep and smoking are key to mental health care, not optional extras, according to the…

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