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AI ‘Fatigue’ Leaves Investors Focused on S&P’s Other 493 Stocks

Bets on artificial intelligence companies have dominated US equity markets for three years, powering a 78% gain. A growing number of investors are now wagering that run, led by the Magnificent Seven, is about to end.

Mounting concerns about AI’s ability to deliver seismic changes on the American economy — and the fat profits that would come with them — has turned investor euphoria about the technology into agita. That’s driving cash into shares of the “other” 493 companies, particularly ones that would benefit most if an expected uptick in economic growth comes about.

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“I call it ‘AI fatigue,’” said Ed Yardeni, president and chief investment strategist at the eponymous Yardeni Research. “I’m tired of it and I suspect a lot of other people are sort of wary of the whole issue.”

The reversal would mark an end to one of the most dominant stretches in market history for such a concentrated swath of the market. Nvidia Corp., Microsoft Corp. and Apple Inc. added trillions in market value since OpenAI’s ChatGPT captivated investors in 2022. Alphabet Inc. and Meta Platforms Inc. were hardly slouches, while second-order companies like Broadcom Inc. and Oracle Corp. got swept up in the exuberance.

The shift, however subtle, has been going on since the S&P 500’s late-October record gave way to a selloff in November. Bloomberg’s gauge for the Magnificent Seven has fallen 2% through Monday’s close since Oct. 29, while the S&P 493 has climbed 1.8%.

The market saw a pullback from momentum names into more defensive and more reasonably priced sectors. The Defiance Large Cap Ex-Magnificent Seven ETF, which launched at the end of 2024, saw six-straight months of inflows to end last year, including a quadrupling in December from November’s level. The ETF, ticker XMAG, rose 15% last year, with the bulk of the advance in the final six months.

The performance of the S&P 493 in 2025 was “impressive,” according to Yardeni. The strategist noted profit margins for the cohort remained elevated and did not “get squeezed” despite the establishment of the Department of Government Efficiency, President Donald Trump’s tariff agenda and signs of weakness in the labor market.

If the economy improves, so too will the prospects for cyclical and growth-orientated sectors, providing ample opportunity for investors looking to move on from the era of Big Tech dominance. Lenders like JPMorgan Chase & Co. and Bank of America Corp. are likely to make gains. Consumer discretionary stocks would benefit from rising confidence among shoppers, who will be more willing to purchase Nike Inc. sneakers or book vacations using Booking Holdings Inc.

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