The A814 Clydeside Expressway will be closed eastbound from the Hayburn Street off-ramp to the Finnieston Street on-ramp.
The closure is scheduled to take place from 11pm on November 17 to 6am on November 18.
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Further closures are set to occur from 8pm on November 20 until 6am on November 21, and again from 11pm on November 21 to 6am on November 22.
The restrictions are expected to remain in place during these times to facilitate the application of high friction surfacing to the carriageway.
Drivers are advised to plan alternative routes as diversions will be in effect.
The diversion will be signposted and will direct traffic via Beith Street, Dumbarton Road, Argyle Street, and Finnieston Street.
Motorists are reminded that the works are weather dependant and subject to cancellation.
