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Is Pfizer Inc. (PFE) A Good Stock To Buy Now?

Is PFE a good stock to buy? We came across a bullish thesis on Pfizer Inc. on r/ValueInvesting by Dismal-Cancel4958. In this article, we will summarize the bulls’ thesis on PFE. Pfizer Inc.’s share was trading at $25.08 as of June 22nd. PFE’s trailing and forward P/E were 19.15 and 8.50 respectively according to Yahoo Finance.

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Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products in the United States and internationally. PFE at approximately $26 per share is increasingly being viewed as a deep value opportunity, with the market pricing in a worst-case scenario driven by post-COVID normalization and looming patent expirations. The stock has declined nearly 60% from pandemic highs as investors focus on collapsing COVID-19 vaccine and Paxlovid revenues, alongside management’s softer 2026 revenue guidance of $59.5–$62.5 billion.

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Additional concern stems from the anticipated patent cliff between 2026 and 2028, particularly for key franchises such as Eliquis and Ibrance, which has led to a narrative that Pfizer’s growth engine is structurally impaired. However, this pessimism overlooks the company’s ongoing transformation and undervalues its long-term earnings power.

On a relative basis, Pfizer trades at roughly 8.8x forward earnings, a steep discount versus peers such as Merck & Co. at ~15.7x and Johnson & Johnson at ~19.2x, despite offering a significantly higher dividend yield of approximately 6.5%. This yield, supported by 17 consecutive years of dividend increases, provides a substantial income buffer while investors wait for a turnaround.

The company has also reshaped its future through the $43 billion acquisition of Seagen, positioning itself as a leader in antibody-drug conjugates and next-generation oncology therapies, a segment with strong long-term growth potential that the market is currently underappreciating.

Beyond oncology, Pfizer holds additional optionality through its GLP-1 pipeline, including approved assets in China and multiple oral candidates in late-stage development, creating meaningful upside if even one program succeeds.

Fiscal 2026 is also expected to be a catalyst-rich year, with more than 20 Phase 3 trials initiating alongside aggressive cost-cutting initiatives aimed at preserving margins despite top-line pressure. Combined, these factors suggest Pfizer is not a value trap but a re-rating candidate, with a potential upside of 2x over the next 3–5 years if pipeline execution and cost discipline converge as expected.

Previously, we covered a bullish thesis on Pfizer Inc. (PFE) by Akim Guerreiro in September 2024, which highlighted dividend resilience, pipeline recovery, and long-term upside driven by strategic acquisitions like Seagen. PFE’s stock price has depreciated by approximately 13.99% since our coverage. Dismal-Cancel4958 shares a similar view but emphasizes peer valuation gaps, patent-cliff concerns, and GLP-1 pipeline optionality as key drivers of a potential 2x upside over 3–5 years.

Pfizer Inc. is not on our list of the 40 Most Popular Stocks Among Hedge Funds. As per our database, 83 hedge fund portfolios held PFE at the end of the first quarter which was 81 in the previous quarter. While we acknowledge the risk and potential of PFE as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than PFE and that has 10,000% upside potential, check out our report about this cheapest AI stock.

Disclosure: None. 

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